Histological evaluation of orthotopic BT142 from mice treated with JHU-083 showed solid IDH1R132H protein expression and decreased pS6(ser235/236) staining (Figure 6B), suggesting that JHU-083 reaches intracranial cells and targets mTORC1 signaling pathway in vivo

Histological evaluation of orthotopic BT142 from mice treated with JHU-083 showed solid IDH1R132H protein expression and decreased pS6(ser235/236) staining (Figure…

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These cells are assumed to contribute to lifelong seasonal gonadal recrudescence and tissue regeneration being the driving factor for carp to have a more than 20-fold higher life expectancy than mammalian models like mouse and hamster (Levine 1997; Hurd and Ralph 1998; Tarn et al

These cells are assumed to contribute to lifelong seasonal gonadal recrudescence and tissue regeneration being the driving factor for carp…

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