Some factors that could, in theory, contribute to this variability are the rate of diffusion of AChR antibodies from the serum into the very small synaptic cleft of each NMJ, the high number of the AChRs within this space that have to be targeted before a deficit in transmission occurs, and synaptic compensatory mechanisms that can be demonstrated in animal models

Some factors that could, in theory, contribute to this variability are the rate of diffusion of AChR antibodies from the…

Continue Reading →

Posted in: PKA